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Furthermore, cytoplasmic dsDNA levels are significantly increased in FLS from RA patients, causing upregulation of genes such as IL-6 , CXCL10 , TNF- , MMP-13 , IL-1 , and IL-8 via a cGAS-dependent mechanism that also disrupts joint homeostasis [22]
The Omada model is built around the idea that care should be continuous, coordinated, and centered around members
Institutional Review Board This study was conducted in accordance with the tenets of the Declaration of Helsinki